The hypoglycemic (blood sugar-lowering)
effect of gymnema leaves was first documented in the late 1920s. This
action is gradual in nature, differing from the rapid effect of many
prescription hypo-glycemic drugs.
Gymnema leaves raise insulin levels, according to research in healthy
volunteers. The leaves are also noted for lowering serum cholesterol
and triglycerides. While studies have shown that a water-soluble
acidic fraction of the leaves provides hypoglycemic actions, it
is not yet clear what specific constituent in the leaves is responsible
for this action.
Some researchers have suggested gymnemic acid as one possible candidates
Further research is needed to clearly determine which constituent
is responsible for this effect. Gurmarin, another constituent of
the leaves, and gymnemic acid have been shown to block sweet taste
in humans.
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