Devil's claw tuber contains three important
constituents belonging to the iridoid glycoside family: harpagoside,
harpagide, and procumbide.
The secondary tubers of the herb contain twice as much harpagoside
as the primary tubers. As such, these secondary tubers contain the
preferable concentration of active ingredients.
Harpagoside and other iridoid glycosides found in the plant may
be responsible for the herb's anti-inflammatory and analgesic actions.
However, research has not entirely supported the use of devil's
claw in alleviating arthritic pain symptoms.
Devil's claw is also considered by herbalists to be a potent bitter.
Bitter principles, like the iridoid glycosides found in devil's
claw, stimulate the stomach to increase the production of acid,
thereby helping to improve digestion.
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